Cryotherapy, vampire facials, salmon DNA — we often find celebrities experimenting with innovative ways to satiate their quest for rejuvenation. The latest celebrity-driven trend on everyone’s radar? NAD+, an IV infusion that has the likes of Hailey Bieber, Kendall Jenner, Jennifer Aniston, and Gwyneth Paltrow swooning over its age-defying results. While it may not be the elixir of life that can turn back the clock, NAD+ hosts properties that aid with ageing slowly and well. But what makes it such a celebrity favourite? Here’s what the experts have to say.
What is NAD+?
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme that is present in all living cells and is essential for energy production, DNA repair, cellular metabolism, and also plays a role in the CLOCK gene system, which governs the sleep-wake cycle.
“The IV infusion therapy involves administering NAD+ directly into the bloodstream, aiming to elevate its levels in the body,” explains Dr Maryam Zamani, facial aesthetics and oculoplastic surgeon, and founder, MZ Skin, London.
Supplements versus infusions
As opposed to oral supplements, NAD+ infusions bypass the digestive system and deliver directly into the bloodstream, potentially allowing for more immediate availability. “These drips typically contain 250 to 750 mg of NAD+, which is slowly infused over 2-4 hours to avoid side effects like nausea,” says Dr Swetha Dilip, aesthetic physician, Cosmesurge Hospital, Dubai. “IV administration allows for significantly higher serum concentrations in the blood — something even high-quality supplements cannot replicate.”
Why NAD+?
Just like vitamins, minerals, and other nutrients, NAD+ is already present in the body and naturally declines as one ages. “As we age, NAD+ levels decline dramatically, by as much as 50 per cent by middle age,” adds Dr Dilip. “This drop has been linked to chronic fatigue, cognitive decline, metabolic syndromes, and accelerated ageing.” The NAD+ IV infusion…
